Effect of anticholinergic preanesthetic medicaments on the requirements of halothane for anesthesia in the cat
Webb, A.I.; McMurphy, R.M.
American Journal of Veterinary Research 48(12): 1733-1735
1987
ISSN/ISBN: 0002-9645 PMID: 3434920 Document Number: 302080
To study the effects of anticholinergics on anesthetic requirements, minimal alveolar concentrations (MAC) for halothane in the cat were measured before and after IM administration of an anticholinergic (atropine sulfate [0.045 mg/kg], glycopyrrolate [0.011 mg/kg], or scopolamine hydrobromide [0.02 mg/kg]) or a physiologic saline control. The study was performed in 8 adult cats, using a randomized-block experimental design. There was no significant difference between the mean MAC obtained before and after administration of any of the test drugs or vs the control values. The mean MAC of halothane in cats was 0.985% atmosphere.