Chemical structure and teratogenic properties. 3. a review of available data on structure-activity relationships and mechanism of action of thalidomide analogues
Jönsson, N.A.
Acta Pharmaceutica Suecica 9(6): 521-542
1972
ISSN/ISBN: 0001-6675 PMID: 4571160 Document Number: 5075
The literature on the teratogenic effect of thalidomide and structurally related compounds is reviewed with emphasis on the mechanistic aspects. Structure-activity relationships are analysed and the various hypotheses put forward to explain the effect are critically discussed.
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