Synthesis and properties of oligonucleotide derivative with P (V) porphyrin

Kitamura, M.; Nimura, A.; Kunimoto, K.; Segawa, H.; Shimidzu, T.

Nucleic Acids Symposium Series 25: 13-14

1991


ISSN/ISBN: 0261-3166
PMID: 1842053
Document Number: 372129
Oligonucleotide derivatives with a P(V)tetraphenylporphyrin at the internucleotidic phosphodiester linkage were synthesized. Their interactions with the complementary oligonucleotide and pyrene-labeled oligonucleotide were investigated. Fluorescence from the porphyrin moiety was strongly quenched by the addition of the pyrene-labeled oligonucleotide and the template oligonucleotide.

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