Oligonucleotide synthesis on a cellulose acetate functionalized with a spacer
Kamaike, K.; Yamakage, S.; Hasegawa, Y.; Ishido, Y.
Nucleic Acids Symposium Series 17: 89-92
1986
ISSN/ISBN: 0261-3166 PMID: 3562284 Document Number: 284123
4-(2-Hydroxyethylsulfonyl)dihydrocinnamate derivative of cellulose acetate (D.S. 1.77) was used for polymer support synthesis of oligonucleotides bearing a phosphodiester function at the 3'-terminal position, taking into consideration that the cellulose derivative is readily soluble in pyridine, but slightly soluble in a solvent such as ethanol.