Immunochemical analysis of water-soluble antigens of the cornea
Belikova, T.V.; Zidorov, S.M.; Formaziuk, V.E.
Biulleten' Eksperimental'noi Biologii i Meditsiny 110(9): 294-295
1990
ISSN/ISBN: 0365-9615 PMID: 2125234 Document Number: 353557
Rabbits were immunized by the water soluble cow cornea antigens. The particle immunochemical identity between cow cornea antigens and cow lens, vitreous humor, aqueous humor, iris, choroid and retina was found in reaction of immunodiffusion in gel. Immune cross reactions between cow cornea antigens and human antigens of different tissue were absent. 9 antigens were indicated by immunoelectrophoresis in cow cornea. Three of them with gamma-mobility locate in epithelium, 2-with gamma-mobility--in endothelium and 4 (two with beta-mobility, and one of alpha 1-mobility and another alpha 2-mobility) in stroma. The possible role of different antigenic composition of cornea is discussed.