Postvaccinal reactions to the administration of a dried staphylococcal vaccine made from water-soluble antigens
Efremova, V.N.; Egorova, N.B.; Kuz'mina, L.A.; Levashov, I.N.; Kobrin, A.I.
Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 2: 47-51
1988
ISSN/ISBN: 0372-9311 PMID: 3364080 Document Number: 325787
An unequivocal regularity in local and systemic reactions to multiple (in 5 injections) administration of lyophilized staphylococcal vaccine prepared from water-soluble antigens has been established in patients and in healthy adults: the number and intensity of reaction decreased after each subsequent injection. A similar tendency has been observed in the vaccinees who were examined for their IgE levels. These data are indicative of the desensitizing action of the vaccine.