Experimental vertical transmission of Japanese encephalitis virus by Culex tritaeniorhynchus and other mosquitoes
Rosen, L.; Lien, J.C.; Shroyer, D.A.; Baker, R.H.; Lu, L.C.
American Journal of Tropical Medicine and Hygiene 40(5): 548-556
1989
ISSN/ISBN: 0002-9637 PMID: 2567124 Document Number: 341035
Vertical transmission of Japanese encephalitis virus to the F1 adult stage was demonstrated in Culex tritaeniorhynchus, Cx. annulus, Cx. quinquefasciatus, and Armigeres subalbatus. Transmission to the F1 larval stage was demonstrated in Cx. pipiens, Aedes vexans, Ae. alcasidi, and Ae. flavus. In Cx. tritaeniorhynchus, vertical transmission rates (the percentage of parent females transmitting to progeny) varied (12-100%). Filial infection rates (the percentage of progeny infected) for a given mosquito virus combination were markedly affected by the interval of time between parental infection and oviposition, suggesting that vertical infection was not transovarial in nature but occurred at oviposition. Filial infection rates for Cx. tritaeniorhynchus also varied widely by family and, as measured in F1 larvae, rates in excess of 20% were observed in a family. Filial infection rates in Cx. tritaeniorhynchus F1 adults were about 4 times lower than those in larvae. Japanese encephalitis virus was sexually transmitted from male to female Cx. tritaeniorhynchus.AS Vertical transmission of Japanese encephalitis (JE) virus to F1 adults was demonstrated in C. tritaeniorhynchus, C. quinquefasciatus and Armigeres subalbatus. Transmission to the F1 larval stage was demonstrated in C. pipiens, Aedes vexans, A. alcasidi and Armigeres flavus. In C. tritaeniorhynchus, vertical transmission rates (the percentage of parent females transmitting to progeny) varied (12-100%). Filial infection rates (the percentage infected) for a given mosquito virus combination were markedly affected by the interval of time between parental infection and oviposition, suggesting that vertical infection was not transovarial in nature but occurred at oviposition. Filial infection rates for C. tritaeniorhynchus also varied widely by family and, as measured in F1 larvae, rates in excess of 20% were observed in a family. Filial infection rates in C. tritaeniorhynchus F1 adults were about 4 times lower than those in larvae. JE virus was sexually transmitted from male to female in C. tritaeniorhynchus.