Cimetidine and ethanol

Papke, J.; Borgmann, H.; Dökert, B.; Bartels, H.; Krause, D.

Zeitschrift für die Gesamte Innere Medizin und ihre Grenzgebiete 44(24): 731-733

1989


ISSN/ISBN: 0044-2542
PMID: 2629368
Document Number: 340872
Cimetidine inhibits hepatic drug metabolism, but its effect on ethanol elimination is less well established. The influence of cimetidine on the kinetics of ethanol is studied with three standardized drinking experiments. Cimetidine had no influence on the absorption or elimination of ethanol. There were significant differences in distribution of ethanol in consequence of inhibition of vascular histamine receptors after cimetidine application.

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