Oleandomycin and its natural and synthetic analogs. II. Structure and properties of oleandomycin B, a new compound of the oleandomycin group
Beliakova, I.G.; Viktorovskiĭ, I.V.; V'iunov, K.A.; Vorontsov, A.M.; Kanev, A.S.
Antibiotiki i Khimioterapiia 34(3): 199-202
1989
ISSN/ISBN: 0235-2990 PMID: 2751375 Document Number: 340051
The revealed regularities of mass spectroscopic disintegration of oleandomycin and its derivatives made it possible to determine analytic criteria for identification of compounds related by their structure to oleandomycin. Analysis of the extracts from oleandomycin fermentation broth filtrates on the basis of the selected group of diagnostic ions showed that along with the main antibiotic there formed during the biosynthesis oleandomycin B, a structurally close minor component. The structure of the substance was assigned and its physico-chemical and biological properties were studied.