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Effect of gradients of monovalent cations on active transport of Ca2+ in the sarcoplasmic reticulum and proteoliposomes

Tugaĭ, V.A.; Diadiusha, G.P.; Usatiuk, P.V.; Zemlianaia, N.N.

Ukrainskii Biokhimicheskii Zhurnal 60(1): 69-74

1988

ISSN/ISBN: 0201-8470
PMID: 3363678
Document Number: 319005
Artificially generated K+ gradient from the sarcoplasmic reticulum vesicles enhances the ATP-dependent Ca2+ transport. The effect is not specific for K+, and is observed when K+ is replaced by Na+ or choline. Dissipation of the K+, Na+, choline gradient does not influence the ATP-dependent Ca2+ transport in proteoliposomes from asolectin and purified Ca2+-ATPase. The K gradient in the presence of valinomycin stimulates the ATP-dependent Ca2+ transport in proteoliposomes.

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