Influence of actinomycin D on the effectiveness of producing ts mutants of the Japanese encephalitis virus
Tikhomirov, E.E.
Voprosy Virusologii 33(3): 335-338
1988
ISSN/ISBN: 0507-4088 PMID: 2459851 Document Number: 312053
Reciprocal competition of viral and cellular matrices of RNA synthesis was demonstrated, as well as a 10-13-fold increase of 3H-uridine incorporation into viral RNAs in the presence of actinomycin D, the inhibiting effect of actinomycin D on virus replication, the dependence of the late stage of Japanese encephalitis virus reproduction upon the host cell, and no positive effect of actinomycin D on generation of Japanese encephalitis virus ts mutants.