A cost-effectiveness analysis of Japanese encephalitis vaccine in Cambodia
Touch, S.; Suraratdecha, C.; Samnang, C.; Heng, S.; Gazley, L.; Huch, C.; Sovann, L.; Chhay, C.S.; Soeung, S.C.
Vaccine 28(29): 4593-4599
2010
ISSN/ISBN: 1873-2518 PMID: 20470803 DOI: 10.1016/j.vaccine.2010.04.086Document Number: 561436
This study aimed to evaluate the cost and effectiveness of introducing a live, attenuated vaccine (SA 14-14-2) against Japanese encephalitis (JE) into the immunization program. The study demonstrated that SA 14-14-2 immunization is cost-effective in controlling JE in Cambodia compared to no vaccination. Averting one disability-adjusted life year, from a societal perspective, through the introduction of SA 14-14-2 through routine immunization, or a combination of routine immunization plus a campaign targeting children 1-5 or 1-10 years of age, costs US$22, US$34 and US$53, respectively. Sensitivity analyses confirmed that there was a high probability of SA 14-14-2 immunization being cost-effective under conditions of uncertainty.
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