Synthesis and antidepressive effects of diaryl-4,6-amino-3-pyridazine analogs of minaprine

Coudert, P.; Rubat, C.; Couquelet, J.M.; Bastide, J.

Il Farmaco; Edizione Scientifica 43(10): 793-800

1988


ISSN/ISBN: 0430-0920
PMID: 3240830
Document Number: 308247
The reaction of 3-chloro pyridazines with various amines led to a series of minaprine analogues. Most of them exhibited significant antidepressant activity. The influence of the substituents attached to the pyridazine ring was discussed.

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