2'-OH-protection by the p-nitrophenylethylsulfonyl group in oligocytidylate synthesis

Pfister, M.; Pfleiderer, W.

Nucleic Acids Symposium Series 18: 165-168

1987


ISSN/ISBN: 0261-3166
PMID: 3697118
Document Number: 301955
A new approach to oligoribonucleotide synthesis has been developed by use of the p-nitrophenylethylsulfonyl group as a new versatile sugar protecting group. The synthesis of 3'-5'- and 2'-5'-cydidylyl-cytidine is performed in high yield.

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