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Antigenic specificity of the neuraminidases of epidemic strains of influenza A/H3N2 viruses circulating in the USSR 1983-1985

Liubovtseva, O.V.; Iakhno, M.A.; Zakstel'skaia, L.Ia.

Voprosy Virusologii 32(3): 283-285

1987

ISSN/ISBN: 0507-4088
PMID: 2445104
Document Number: 299513
The antigenic properties of neuraminidase of the epidemic strains of 1983-1985 were studied by means of lectin test and thiobarbituric method using polyclonal sera and monoclonal antibody. Populations of the viruses with respect to antigenic relationships of neuraminidase were shown to be heterogeneous. A considerable portion of the strains occurring in 1985 underwent antigenic drift from the reference A/Philippines/2/82 strain. The epidemic novelty of some strains was due to changes in only one supercapsid protein-neuraminidase.

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