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Microbial transformation of azacarbazoles. VIII. Production of 14C-labelled benzo-alpha-iso-carbolines by permeabilized cells of Kitasatosporia setae strain

Peczyńska-Czoch, W.

Archivum Immunologiae et Therapiae Experimentalis 35(2): 139-142

1987

ISSN/ISBN: 0004-069X
PMID: 3447530
Document Number: 298949
N-1 methylation of benzo-alpha-carbolines performed with Kitasatosporia setae strain yields corresponding benzo-alpha-iso-carbolines, compounds demonstrating relatively strong cytostatic and antitumor properties. To obtain radioactive benzo-alpha-iso-carbolines required for the further studies of their mode of antitumor action, a simple and useful method of the preparation of 14C-labelled compounds by microbial means has been elaborated.

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Peczyńska-Czoch, W.; Mordarski, M.; Kaczmarek, L.; Nantka-Namirski, P. 1987: Microbial transformation of azacarbazoles. I. N-methylation of alpha-, beta-, and gamma-carbolines by Kitasatosporia setae strain Archivum Immunologiae et Therapiae Experimentalis 35(2): 89-95
Peczyńska-Czoch, W. 1987: Microbial transformation of azacarbazoles. V. Studies on N-1 methylation of 4-methyl-alpha-carboline by Kitasatosporia setae strain Archivum Immunologiae et Therapiae Experimentalis 35(2): 117-124
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