Synthesis and antihyperlipidemic activities of benzylidenebenzofuran- 3 (2H) ones

Hauad, L.; Fulcrand, P.; Chevallet, P.; Darmanaden, R.; Serrano, J.J.; Castel, J.

Annales Pharmaceutiques Francaises 45(6): 459-465

1987


ISSN/ISBN: 0003-4509
PMID: 3504121
Document Number: 292400
In this article, the synthesis and antihyperlipidemial activities (towards triglycerides, cholesterol and serum total lipid contents) of a series of 2-[4'(1"-carbethoxyisopropyloxy) benzylidene] benzofuran-3-one is reported. Among these compounds, 2-[4'-(1"carbethoxy isoproplyoxy) benzylidene] 7-chloro 4,6-dimethoxy benzofuran 3-one exert a most favorable effect than fenofibrate.

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