Effect of zinc source and picolinic acid on 65Zn uptake in an in vitro continuous-flow perfusion system for pig and poultry intestinal segments
Hill, D.A.; Peo, E.R.; Lewis, A.J.
Journal of Nutrition 117(10): 1704-1707
1987
ISSN/ISBN: 0022-3166 PMID: 3668684 Document Number: 290131
Twenty weanling pigs and 14 9-week-old broiler chickens were used in 3 continuous-flow perfusion experiments in vitro using non-everted intestinal sacs to estimate differences in 65Zn absorption due to location within the intestinal tract, evaluate 65Zn uptake from ZnCl2 and zinc methionine (ZnMet) with or without added picolinic acid (PA) in pig intestinal sacs and evaluate 65Zn uptake from ZnCl2 and ZnMet in chicken intestinal sacs. There were no differences in 65Zn uptake due to gut segment position in the pigs. A Zn source x PA interaction was observed for 65Zn uptake into the pig gut tissue and for 65Zn uptake to the serosal side of the gut sacs. Total 65Zn absorption in the pig gut sacs from the 2 Zn sources was not different, but the addition of a 5 M ratio of PA to Zn depressed 65Zn absorption. There were no differences in total 65Zn absorption or 65Zn uptake in poultry gut sac tissue. There was, however, greater uptake of 65Zn from ZnCl2 to the serosal side of the sacs than from ZnMet. The results indicate that 65Zn from ZnCl2 and ZnMet is similar in total absorption and that the addition of PA depresses Zn uptake.