Effect of brain acid extract products in inbred mice on 3H-diazepam reception

Blednov, I.A.; Fedoseev, I.L.; Bogdanov, N.N.; Gordeĭ, M.L.; Seredenin, S.B.

Biulleten' Eksperimental'noi Biologii i Meditsiny 102(9): 294-296

1986


ISSN/ISBN: 0365-9615
PMID: 3019448
Document Number: 276954
The influence of brain acid extract products, isolated by high-performance liquid chromatography on H3-diazepam binding was investigated in synaptosomal membranes of C57BL/6 and BALB/c mice. Fractions with stimulatory and inhibitory activity were isolated. Quantitative and qualitative differences in the effects and structure of ACTH-immunoreactive peptide fractions under study were established.

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