Effect of a single ethanol administration on the behavior and the RNA-synthesizing activity of the cell nuclei of the cerebral cortex of the rat
Beliavtseva, L.M.; Kulikova, O.G.; Shabanov, P.D.; Razumovskaia, N.I.
Farmakologiia i Toksikologiia 47(3): 38-41
1984
ISSN/ISBN: 0014-8318 PMID: 6203776 Document Number: 239448
A single intraperitoneal injection of ethanol (2 g/kg) disturbed the learning and performance of one trial passive avoidance task and decreased (by 14 %) the level of RNA-synthesizing activity of brain cortical synaptosomes in rats. The data obtained are discussed in accordance with the hypothesis that ethanol affects synaptic transmission in the central nervous system.
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