Study on tissue transfer of ceftriaxone in the field of obstetrics and gynecology
Matsui, Y.; Noda, M.; Kohara, T.
Japanese Journal of Antibiotics 37(12): 2320-2327
1984
ISSN/ISBN: 0368-2781 PMID: 6098724 Document Number: 232947
Ceftriaxone (Ro 13-9904, CTRX) was studied about the tissue transfer in the gyneco-obstetric field and the following results were obtained. The transfer of CTRX into the uterine tissues and adnexa was favorable following an intravenous injection with 1 g. The mean serum level 1 hour after administration was 123.3 micrograms/ml while the tissue level ranged from 26 to 48 micrograms/g. The level in the pelvic dead space exudate reached a peak 3 to 6 hours after administration and got higher than the serum level at 5 to 6 hours.
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