Development and characterization of a monoclonal antibody (Aby 6C6) that distinguishes medullary from cortical thymocytes
Krawiec, D.R.; Muscoplat, C.C.
American Journal of Veterinary Research 45(3): 499-505
1984
ISSN/ISBN: 0002-9645 PMID: 6370058 Document Number: 229424
A hybridoma (6C6) producing antibodies with specificities to canine thymocyte surface antigens was produced using standard fusion techniques. The Aby 6C6 has affinity for medullary thymocytes, bone marrow cells, T- and B-peripheral lymphocytes, and monocytes. The Aby 6C6 appears to have 2 heavy chains with different molecular weights, an isoelectric focusing pattern consistent with monoclonality, and is an immunoglobulin G2b antibody with a kappa light chain.