Necrotic enteritis in piglets due to Clostridium perfringens type "C"
Sidoli, L.; Guarda, F.
Schweizer Archiv für Tierheilkunde 124(11): 557-565
1982
ISSN/ISBN: 0036-7281 PMID: 6294823 Document Number: 191450
The disease affected mostly piglets aged 7-12 days, with sporadic cases appearing after weaning. In about half the cases death was sudden. In the remainder, diarrhoea occurred, with asthenia and emaciation. PM lesions were necrotic enteritis of the small intestine, and sometimes the colon and caecum, with fibrinous, necrotic membranes in these areas. Peyer's patches were hyperplastic. There was pulmonary oedema and some alveolar emphysema. C. perfringens type C was isolated from intestinal lesions. Antibiotic treatment only partly reduced mortality. Inoculation of sows in infected herds with toxoid, 45 and 15 days before farrowing, prevented reappearance of the disease, though sometimes it was necessary also to inoculate the pigs, s/c or i/p, soon after birth with toxoid.