Structural differences of C-terminal fragment of the alpha-subunits of rabbit muscle aldolase in normal animals and in experimental atherosclerosis
Antonenko, R.D.; Litvinenko, L.T.; Gulyĭ, M.F.
Ukrainskii Biokhimicheskii Zhurnal 54(5): 514-518
1982
ISSN/ISBN: 0201-8470 PMID: 7135508 Document Number: 191204
The COOH-terminal BrCN fragment of the aldolase alpha-subunit from muscles of rabbits in norm and under atherosclerosis was studied by the method of dansyl-fingerprints in a silicagel and polyamide thin layer. It is shown that under atherosclerosis the amount of peptides in the fragment under study increases and the topography of two of them changes. The content of lysine, serine and valine enhances in it. The results evidence for structural differences in C-terminal fragment of aldolase alpha-subunits in muscles of rabbits in norm and under experimental atherosclerosis.