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Concentration of some proteinase inhibitors: alpha 1-antitrypsin and alpha 2-macroglobulin in rabbit blood serum in two models of experimental atherosclerosis

Grabowska-Bochenek, R.; Drózdz, M.; Kopieczna-Grzebieniak, E.; Piekarski, M.

Acta Biochimica Polonica 37(1): 125-127

1990

ISSN/ISBN: 0001-527X
PMID: 1708185
Document Number: 357332
In rabbits with experimental atherosclerosis induced by a cholesterol-rich diet, alpha 1-antitrypsin concentration was decreased as compared with control, by 34%, whereas alpha 2-macroglobulin concentration was increased by 86%. In animals fed a methionine-rich diet changes in concentration of both inhibitors involved in elastase metabolism were but slight, if any.

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