The NADP binding site on rabbit muscle aldolase
Matteuzzi, M.; Bellini, T.; Bergamini, C.M.; Dallocchio, F.
Biochemistry International 10(1): 53-62
1985
ISSN/ISBN: 0158-5231 PMID: 3985986 Document Number: 242758
Rabbit muscle aldolase binds NADPH with a 1:1 stoichiometry and with a dissociation constant 18 microM. Three sites of the dinucleotide are involved in the binding: the adenosyl diphosphate moiety, the nicotinamide-ribose, and the nicotinamide ring. These data show the existence of a specific dinucleotide binding site in the aldolase molecule.
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