Effects of a gonadotropic hormone of teleost fish on the adenylate cyclase of rat ovary and on its stimulation by ovine gonadotropins
Salmon, C.; Delerue-Le Belle, N.; Fontaine, Y.A.
Comptes Rendus des Seances de la Societe de Biologie et de ses Filiales 176(6): 787-794
1982
ISSN/ISBN: 0037-9026 PMID: 6220787 Document Number: 186691
Carp gonadotropin (cGTH) stimulated adenylate cyclase from 20-24 day old (but not 16-18 day old) rat ovaries; its subunits were inactive. Carp GTH (but not its subunits) increased the apparent KD for oFSH but not for oLH. These results suggest that cGTH mainly interacts with FSH sensitive adenylate cyclase-receptor systems, with an efficiency about 6 X 10(3) times lower than oFSH itself.