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The selectivity of amino acid and peptide amidination with O-methylisourea

Wojciechowska, H.; Zgoda, W.; Borowski, E.

Acta Biochimica Polonica 29(3-4): 197-204

1982

ISSN/ISBN: 0001-527X
PMID: 7158170
Document Number: 186601
Selectivity of amidination using ornithine as model amino acid was investigated in detail. The results obtained were taken advantage of for studying the reactions with other polyfunctional amino acids: beta-tyrosine, isoserine, 2,3-diaminopropionic acid, 2,6-diamino-7-hydroxyazelaic acid and with the pentapeptide amide, edeine A. It was found that, if the appropriate conditions are maintained, selective amidination of more basic amino groups of polyamino compounds is possible when these groups are bound to the primary alkyl.

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Schoofs, P.G.; Geysen, H.M.; Jackson, D.C.; Brown, L.E.; Tang, X.L.; White, D.O. 1988: Epitopes of an influenza viral peptide recognized by antibody at single amino acid resolution Journal of Immunology 140(2): 611-616
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Page, C.M.; Inglis, M.S.; Wheatley, D.N. 1982: The intracellular acid-extractable (acid-soluble) amino acid pool in mammalian cells: 4 An hypothesis to explain the effects of preloading on the exchange of amino acids across the cell membrane Cytobios 34(134): 105-123
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Neurath, A.R.; Pride, M.W.; Strick, N.; Thanavala, Y.M. 1991: Toleration of amino acid substitutions within hepatitis B virus envelope protein epitopes established by peptide replacement set analysis. I. Region S(139-147) Peptide Research 4(3): 199
Thanavala, Y.M.; Hay, F.C.; Stevens, V.C. 1980: Affinity, cross-reactivity and biological effectiveness of rabbit antibodies against a synthetic 37 amino acid C-terminal peptide of human chorionic gonadotrophin Clinical and Experimental Immunology 39(1): 112-118
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Nicholas, J.A.; Levely, M.E.; Mitchell, M.A.; Smith, C.W. 1989: A 16-amino acid peptide of respiratory syncytial virus 1A protein contains two overlapping T cell-stimulating sites distinguishable by class Ii MHC restriction elements Journal of Immunology 143(9): 2790-2796
Nowak, K.; Malarska, A.; Ostropolska, L.; Kuczek, M.; Zowmir, O.; Slomińska, A.; Wolny, M.; Baranowski, T. 1976: Amino acid sequence of human muscle glyceraldehyde-3-phosphate dehydrogenase. Isolation and amino acid sequences of tryptic peptides Acta Biochimica Polonica 23(2-3): 127-138
Katrukha, G.S.; Silaev, A.B.; Trifonova, Z.P.; Diarra, B.; Lomakina, N.N. 1978: Quantitative amino acid makeup and the characteristics of the amino groups of ristomycin and the products of its partial acid hydrolysis Antibiotiki 23(1): 38-43
Romantsev, F.E.; Prozorovskiĭ, V.N.; Kozlov, E.A.; Karpov, D.A.; Trebukhina, E.L. 1989: Determination of the amino acid composition of cartilage and creatine phosphokinase isoenzymes with the use of phenylthiocarbamyl amino acid derivatives Voprosy Meditsinskoi Khimii 35(3): 71-75
Kawai, C. 1989: A study on amino acid solutions for postoperative parenteral nutrition--evaluation in terms of surgical stress, amino acid composition and its doses Nihon Geka Gakkai Zasshi 90(8): 1140-1153
Trikulenko, A.V. 1993: Characteristics for determining nonpolar amino acid residues in amino acid sequences of certain globular proteins Molekuliarnaia Biologiia 27(2): 320-322
Dölp, R.; Grünert, A.; Schmitz, E.; Ahnefeld, F.W. 1987: Clinical studies of peripheral venous parenteral nutrition. Effect of a 3.5% amino acid solution on postoperative metabolism with special reference to amino acid homeostasis Infusionstherapie und Klinische Ernahrung 14 Suppl. 1: 10-16
Asano, Y.; Komeda, H.; Okazaki, S.; Yamane, T. 2008: Discovery of D-stereoselective amino acid amidases and their use in kinetic resolution of amino acid amides Seikagaku. Journal of Japanese Biochemical Society 80(4): 294-299