A collagen-like glycoprotein from elastin-rich tissues
Gibson, M.A.; Cleary, E.G.
Biochemical and Biophysical Research Communications 105(4): 1288-1295
1982
ISSN/ISBN: 0006-291X PMID: 6285903 Document Number: 184898
Extracts of bovine aorta and nuchal ligament contain several large glycoproteins. The major glycoprotein species was isolated and was shown to be collagenase sensitive with an apparent MW of 140,000 daltons. The protein exists in disulfide-bonded aggregates, contains hydroxyproline and hydroxylysine in 1:1 ratio and is unlike any of the known collagen types in amino acid analysis. Its presence in ligament extracts indicates that it is not derived from basement membranes. This protein is probably not derived from the microfibrillar components of the elastic tissues.