Long-term evaluation of collagen and elastin following infrared (1100 to 1800 nm) irradiation
Tanaka, Y.; Matsuo, K.; Yuzuriha, S.
Journal of Drugs in Dermatology Jdd 8(8): 708-712
2009
ISSN/ISBN: 1545-9616 PMID: 19663107 Document Number: 13391
Infrared irradiation stimulates collagen production, but histological differences in its long-term effects on type I versus type III collagen and elastin in human tissue are unclear. To investigate the effects of infrared irradiation. In vivo human tissues in sun-protected and sun-exposed areas were irradiated with infrared. Histological samples were analyzed, and visual changes were assessed up to 90 days post-treatment. Infrared irradiation provided long-term increases in collagen and elastin levels on post-irradiation days 30, 60 and 90 compared to controls. Significant increases in type I collagen persisted until 30 and 60 days, and in sun-protected and exposed skin biopsies, respectively. Significant increases in type III collagen and elastin persisted until 90 days in both sun-protected and sun-exposed skin biopsies. Infrared irradiation provides safe and effective long-term stimulation of collagen I and III and elastin, which is beneficial for improving skin laxity and wrinkles.
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