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Study of influenza virus interaction with T- and B-lymphocytes

Stopchanskaia, A.G.; Novitskaia, V.I.; Mokienko, S.V.; Malikova, M.V.; Prilutskaia, N.I.

Voprosy Virusologii 5: 558-561

1981

ISSN/ISBN: 0507-4088
PMID: 6977947
Document Number: 181264
B and T lymphocytes of a healthy and immune donor inactivate influenza virus and form "caps" in the presence of the latter. The process of "cap formation" by lymphocytes of a healthy donor terminated in separation of the "cap" with virions adsorbed on multiple microspikes. The virions attached to lymphocytes of the immune donor concentrate in the area of the "cap" which apparently is not rejected from the cell. B lymphocytes of normal and T lymphocytes of immune donors seem to form the "caps" more actively. Influenza virions penetrate lymphocytes of immune donors more rapidly and in greater numbers.

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