Interaction of plasma membranes with influenza virus. V. Changes in creatine phosphokinase activity
Krizanová, O.; Svatosová, Z.
Acta Virologica 19(2): 97-105
1975
ISSN/ISBN: 0001-723X PMID: 239570 Document Number: 89419
A decrease in creatine phosphokinase (CPK) activity was observed in plasma membranes (PM) treated with native A/WSN influenza virus but not in PM treated with heat-inactivated virus. The decrease in CPK activity depended on the amount of virus added to PM, on the pH of the medium and on the quality of the isolated PM. It was evident already after 10 minutes of incubation at 37 degrees C. The possible mechanism of the inhibition of the CPK activity and the relation to changes in adenosine triphosphatase (ATPase) activity and to fusion are discussed.