Antimicrobial activity of N- (4-phenyl-3-methyl-2-butenyl) carbonylhydroxymethylpiperidinium chloride
Pis'ko, G.T.; Gudz', O.V.; Borisova, E.V.
Mikrobiolohichnyi Zhurnal 43(1): 119-121
1981
ISSN/ISBN: 0201-8462 PMID: 7253972 Document Number: 169433
The range of the antimicrobial effect was studied for N-(4-phenyl-3-methyl-2-butenyl) carboxymethylpyridinium-chloride relative to gram-positive, gram-negative bacteria and fungi. The preparation is effective with respect to gram-positive, certain gram-negative bacteria and yeast-like fungi of the Candida genus. The compound under study manifests the highest activity in the moderate alkaline medium (pH 7.2-7.8) and lowers the activity in the presence of 10% horse serum and with an increase in the inoculation dose of the microbial material.