Antiviral, antibacterial and antitumor activity of the hydrazide and the ethyl ester of 2,2'-anhydro-1- (beta-D-arabinofuranosyl) -orotic acid
Golovinsky, E.; Galabov, A.S.; Stankevich, E.Y.; Karparov, A.; Maneva, L.; Grancharov, K.; Chakova, N.; Sniker, D.Y.; Angelov, I.; Velichkova, E.
Arzneimittel-Forschung 30(12): 2087-2090
1980
ISSN/ISBN: 0004-4172 PMID: 7011329 Document Number: 162243
It has been demonstrated that the hydrazide and the ethyl ester of 2,2'-anhydro-1-(beta-D-arabinofuranosyl) orotic acid inhibit selectively the multiplication of some DNA-containing viruses (PsRV, VV, AdV5), suppress the growth of E. coli and St. aureus in vitro and exhibit an antitumor effect with Lewis lung carcinoma and sarcoma 298.
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