Antibacterial and antiviral activity of the polychloroethyl- and beta,beta-dichlorovinylamides of carboxylic acids
Lidina, P.V.; Mirskova, A.N.; Kichigina, E.L.; Shashnian, B.A.; Voronkov, M.G.
Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 7: 76-80
1979
ISSN/ISBN: 0372-9311 PMID: 474009 Document Number: 153083
A number of compounds having antiviral and antibacterial (antistaphylococcal) activity was found in the beta,beta-dichlorvinyl- and alpha-chlor(alpha-oxy)-beta,beta,beta-trichlorethylamide series of carboxylic acids. The antistaphylococcal activity of the compounds under study was found to depend, to a certain extent, ontheir chemical structure, whereas no such dependence was established in respect of their antiviral activity. In the treatment of combined influenza-staphylococcal infection a decrease in antistaphylococcal effect was observed, while antiviral activity remained stable.