Effect of several anti-arrhythmic substances on ion currents in from atrium
Porotikov, V.I.; Filippov, A.K.; Mashkovskiĭ, M.D.; Zaĭtseva, K.A.
Farmakologiia i Toksikologiia 42(2): 142-147
1979
ISSN/ISBN: 0014-8318 PMID: 437081 Document Number: 153300
On trabeculae of the frog's atrium it is shown by the method of the potential fixation with the use of a double saccharose bridge that novocainamide, quinidine and oxylidine mainly reduce the steady output membrane current and virtually have no effect on the input peak current. And, conversely, novocain significantly suppresses the input peak current and affects but little the steady membrane current.