Pro-arrhythmic effects of anti-arrhythmic agents. Study methods and difficulties in analysis
Libersa, C.; Caron, J.; Guedon-Moreau, L.; Lacroix, D.
Therapie 47(5): 363-365
1992
ISSN/ISBN: 0040-5957 PMID: 1299972 Document Number: 395134
We link two-allele population models by Haldane and Fisher with Kimura's diffusion approximations of the Wright-Fisher model, by considering continuous-state branching (CB) processes which are either independent (model I) or conditioned to have constant sum (model II). Recent works by the author allow us to further include logistic density-dependence (model III), which is ubiquitous in ecology. In all models, each allele (mutant or resident) is then characterized by a triple demographic trait: intrinsic growth rate r, reproduction variance 2006 Elsevier Inc. All rights reserved.