Antithyroid-antibody activity in the snyovial fluid of patients with various arthritides
Blake, D.R.; McGregor, A.M.; Stansfield, E.; Smith, B.R.
Lancet 2(8136): 224-226
1979
ISSN/ISBN: 0140-6736 PMID: 89333 Document Number: 141347
Microsomal and thyroglobulin autoantibody activity was detected in synovial fluid from 34 of 50 patients with various arthritides (rheumatoid arthritis, ankylosing spondylitis, osteoarthrosis, and gout). Serum from only 4 of these patients showed thyroid-autoantibody activity and the serum titers were considerably lower than the synovial-fluid titers. Thyroid autoantibody is probably produced locally in the joints of these patients.
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