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Antigenic specificity of influenza type a virus hemagglutinin by the method of radioimmunological quantitative analysis

Berezina, O.N.; Blokha, V.V.; Iamnikova, S.S.; Iakhno, M.A.; Zakstel'skaia, L.I.

Voprosy Virusologii 2: 160-165

1978

ISSN/ISBN: 0507-4088
PMID: 78586
Document Number: 138461
The use of a test system o fa highly purified, antigenically homogeneus hemagglutinin of influenza A/MRC-11 virus and monospecific antiserum permitted to evaluate the potentials of competitive radioimmunoassay in model experiments investigating the antigenic characteristics and content of influenza A (H3N2) virus hemagglutinin. The method proved to be sufficiently specific to differentiate influenza virus strains by antigenic determinants of hemagglutinin, as well as highly sensitive, detecting very small (down to 1 ng) amounts of H3 hemagglutinin in a sample.

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