5-Fluorouracil O-beta-D-glucuronide as a newly synthesized chemically modified, nontoxic anticancer drug
Baba, T.; Kidera, Y.; Kimura, N.T.; Aoki, K.; Kamura, T.; Taniguchi, S.; Nishikawa, K.
Gan 69(2): 283-284
1978
ISSN/ISBN: 0016-450X PMID: 680467 Document Number: 132868
Document emailed within 1 workday
Related Documents
Sass, J.O.; Masgrau, E.; Saurat, J.H.; Nau, H. 1995: Metabolism of oral 9-cis-retinoic acid in the human. Identification of 9-cis-retinoyl-beta-glucuronide and 9-cis-4-oxo-retinoyl-beta-glucuronide as urinary metabolites Drug Metabolism and Disposition: the Biological Fate of Chemicals 23(9): 887-891Sahoo, S.K.; Sahoo, S.K.; Behera, A.; Patil, S.V.; Panda, S.K. 2013: Formulation, in vitro drug release study and anticancer activity of 5-fluorouracil loaded gellan gum microbeads Acta Poloniae Pharmaceutica 70(1): 123-127
Hemmer, J.; Kreidler, J.; Kraft, K.; Schön, E. 1994: Monitoring of anticancer drug effects in vivo by serial DNA flow cytometry of oral carcinomas treated by intra-arterial 5-fluorouracil/cisplatin induction chemotherapy Anticancer Research 14(5b): 2077-2083
Kabilova, T.O.; Vladimirova, A.V.; Repkova, M.N.; Ven'iaminova, A.G.; Chernolovskaia, E.L.; Vlasov, V.V. 2006: Silencing of c-myc gene expression by enzymatically and chemically synthesized siRNAs Molekuliarnaia Biologiia 40(6): 1037-1046
Deibel, M.R.; Lobl, T.J.; Yem, A.W. 1989: A technique for rapid purification of low yield products: biotinylation of chemically synthesized proteins on-resin Peptide Research 2(2): 189-194
Kára, J.; Borovicka, M.; Liebl, V.; Smolíková, J.; Ubik, K. 1986: A novel nontoxic alkyl-phospholipid with selective antitumor activity, plasmanyl-(N-acyl)-ethanolamine (PNAE), isolated from degenerating chick embryonal tissues and from an anticancer biopreparation cACPL Neoplasma 33(2): 187-205
Bittle, J.L.; Houghten, R.A.; Alexander, H.; Shinnick, T.M.; Sutcliffe, J.G.; Lerner, R.A.; Rowlands, D.J.; Brown, F. 1982: Protection against foot-and-mouth disease by immunization with a chemically synthesized peptide predicted from the viral nucleotide sequence Nature 298(5869): 30-33
Sommadossi, J.P.; Cross, D.S.; Gewirtz, D.A.; Goldman, I.D.; Cano, J.P.; Diasio, R.B. 1985: Evidence from rat hepatocytes of an unrecognized pathway of 5-fluorouracil metabolism with the formation of a glucuronide derivative Cancer Research 45(6): 2450-2455
McIlwain, D.L.; Hoke, V.B. 1988: Allocation of newly synthesized proteins in spinal motoneurons Revue Neurologique (Paris) 144(11): 697-700
Tongia, S.K.; Trivedi, C.P.; Matkar, S.V.; Chouhan, R.S.; Kaushal, R. 1981: Neuropharmacological actions of some newly synthesized Mannich bases Indian Journal of Physiology and Pharmacology 25(3): 269-273
Detiuk, E.S.; Turkevich, N.M.; Avgustinovich, M.S.; Kolosova, L.G.; Vyshemirskaia, L.D. 1976: Antithyroid activity of various newly synthesized 1,3-thiazine derivatives Problemy Endokrinologii 22(4): 103-107
Sato, W.; Fukazawa, N.; Suzuki, T.; Yusa, K.; Tsuruo, T. 1991: Circumvention of multidrug resistance by a newly synthesized quinoline derivative, MS-073 Cancer Research 51(9): 2420-2424
Gauchy, C.; Kemel, M.L.; Glowinski, J.; Besson, M.J. 1981: In vivo release of newly synthesized GABA in the basal ganglia of the cat Advances in Biochemical Psychopharmacology 29: 183-191
Mitcheva, M.; Vitcheva, V.; Manolov, I.; Valkova, I. 2002: Effects of two newly synthesized 4-hydroxycoumarin derivatives (4-OHC) on isolated rat hepatocytes Methods and Findings in Experimental and Clinical Pharmacology 24(6): 345-349
Igarashi, T.; Yamamoto, M.; Yamada, M.; Ogata, E.; Katsuragi, S. 1982: Application of newly synthesized 1-34 human parathyroid hormone for diagnostic tests Pharmatherapeutica 3(2): 79-85
Kleinrok, Z.; Kolasa, K.; Mastalerz, P.; Kafarski, P. 1986: Preliminary pharmacological evaluation of newly synthesized derivatives of phosphonoamino acids Polish Journal of Pharmacology and Pharmacy 38(5-6): 435-442
Raĭnova, L.; Staneva, D.; Chakŭrova, L. 1982: Comparative pharmacological study of efortil with a newly synthesized derivative of 2-aminotetralin Eksperimentalna Meditsina i Morfologiia 21(4): 183-186
Karaiskos, K.S.; Boukis, M.A.; Piperingos, G.D.; Kitsopanides, J.; Souvatzoglou, A.; Koutras, D.A. 1984: The treatment of nontoxic goitre with thyroxine and beta-blockers Acta Endocrinologica. Supplementum 265: 41-42
Ohtani, H.; Arimoto, Y.; Nishio, K.; Kanamiya, Y.; Oba, H.; Adachi, K.; Shintani, M.; Nakamura, R.; Yui, S. 2008: Efficacy and toxicity of fluorouracil, leucovorin plus oxaliplatin (FOLFOX4 and modified FOLFOX6) followed by fluorouracil, leucovorin plus irinotecan(FOLFIRI)for advanced or metastatic colorectal cancer--case studies Gan to Kagaku Ryoho. Cancer and ChemoTherapy 35(10): 1769-1774
Biesalski, H.K.; Schäffer, M. 1997: Comparative assessment of the activity of beta-carotene, retinoyl-beta-D-glucuronide and retinoic acid on growth and differentiation of a human promyelocytic leukemia cell line HL-60 International Journal for Vitamin and Nutrition Research. Internationale Zeitschrift für Vitamin- und Ernahrungsforschung. Journal International de Vitaminologie et de Nutrition 67(5): 357-363