Synthesis and anticonvulsant activity of new acylthiosemicarbazides and thiazolidones

Gürsoy, A.; Karali, N.

Farmaco 50(12): 857-866

1995


ISSN/ISBN: 0014-827X
PMID: 8634077
Document Number: 1240
A number of 1-(3-phenyl-4(3H)-quinazolinone-2-ylmercaptoacetyl)-4-substituted thiosemicarbazide and 2-(3-phenyl-4(3H)-quinazolinone-2-ylmercaptoacetylhydrazono)-3-substituted 4-thiazolidone derivatives were synthesized and evaluated for anticonvulsant activity . Some of the tested compounds showed significant activity against MES and ScMet induced seizures.

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Synthesis and anticonvulsant activity of new acylthiosemicarbazides and thiazolidones