Nomogram for the determination of the size of protein molecules and approximation of their molecular weights
Ottesen, B.V.; Korovnikov, K.A.
Molekuliarnaia Biologiia 11(5): 1176-1181
1977
ISSN/ISBN: 0026-8984 PMID: 618343 Document Number: 120601
A nomograph is suggested using which one can determine from the molecular weight and one of the dimensions of the molecule the remaining dimension and the axial ratio for the ellipsoid of rotation with the volume equivalent to the volume of the protein molecule. The nomograph permits to determine molecular weight from the molecular size of the dry protein and of the protein dissolved in water. From the molecular size of the dry protein corresponding dimensions for the protein molecule in an aqueous solution can be obtained. At last the nomograph can help to evaluate the correctness of the literature data and experimental data on the molecular sizes of proteins and on their molecular weights.