Free radical peroxidation of liver mitochondrial and microsomal phospholipids in rat postnatal development
Lankin, V.Z.; Tikhaze, A.K.; Kotelevtseva, N.V.; Markelova, V.I.
Biokhimiia 42(7): 1292-1297
1977
ISSN/ISBN: 0320-9725 PMID: 20167 Document Number: 114157
Activities of both non-enzymic (ascorbate-dependent) and enzymic NADPH-dependent) peroxidation of microsomal and mitochondrial phospholipids are found to be increased in rat liver during postnatal development. It is suggested, that microsomal NADPH-dependent phospholipid dioxygenase forming a chemical modification of membrane polyenic acyls, can be a factor regulating the activities of membrane-linked enzymes under normal physiological processes.