Free radical scavenging and lipid peroxidation of Thai medicinal plants used for diabetic treatment
Steinrut, L.; Itharat, A.; Ruangnoo, S.
Journal of the Medical Association of Thailand 94(Suppl 7): S178-S182
2011
ISSN/ISBN: 0125-2208 PMID: 22619926 Document Number: 12710
To investigate antioxidant activities of some selected plants used to treat diabetic patients by Thai folk doctors. Ten Thai plants were selected, macerated and extracted with 95% ethanol. DPPH scavenging and lipid peroxidation assays were used to test the antioxidant activities of the extracts. Mammea siamensis (Saaraphee), Tacca chantrieri (Narapusri) and Albizia myriophylla (Cha Em Thai) showed the highest antioxidant activity on DPPH radical assay (EC50 = 10.17, 10.24 and 14.45 microg/ml, respectively). Mimussops elengi (Pikun), M. siamensis (Saaraphee) and A. myriophylla (Cha Em Thai) exhibited the highest antioxidant activity by lipid peroxidation assay (IC50 0.39, 0.43 and 0.70 microg/ml, respectively). Six often plant extracts showed antioxidant activity on both assays (IC50 < 20 microg/ml). These plant extracts containing in Thai folklore antidiabetic medicine, which showed high antioxidant activity, may be used effectively for the treatment of diabetic patients.