Immunological selection of tumour cells which have lost SV40 antigen expression
Mora, P.T.; Chang, C.; Couvillion, L.; Kuster, J.M.; Mcfarland, V.W.
Nature 269(5623): 36-40
1977
ISSN/ISBN: 0028-0836 PMID: 197429 Document Number: 110837
In an already tumorigenic, spontaneously transformed mouse cell, after further transformation by SV-40, the virus-specific antigenic function becomes dominant. By transplanation into syngeneic mice SV-40 antigen negative revertant tumor cells can be selected out.
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