Plasmodium berghei: characteristics of a selected population of small free blood stage parasites
Krier, J.P.; Hamburger, J.; Seed, T.M.; Saul, K.; Green, T.
Tropenmedizin und Parasitologie 27(1): 82-88
1976
ISSN/ISBN: 0303-4208 PMID: 769270 Document Number: 105975
The characteristics of a selected population of small blood stage parasites obtained by differential centrifugation of a population of P. berghei parasites freed from the blood of infected mice or rats by continuous flow sonication are described. About 10% of these free parasites are merozoites; many others are transitional forms having some merozoite characteristics. The parasite preparations are infectious and sufficiently resistant to incubation at 37.degree. to be useful experimentally. Disc gel electrophoresis analysis indicates that these small parasites differ in composition from an unselected intraerythrocytic P. berghei population.