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Absorption studies with purines. Part 2. in vitro experiments with a diffusion apparatus

Heppt-Becker, I.; Schunack, W.

Arzneimittel-Forschung 26(4): 473-476

1976

ISSN/ISBN: 0004-4172
PMID: 989000
Document Number: 102309
Various purines were investigated with the Desaga Resomat II, their diffusion speed constants calculated according to Stricker and compared with one another. The drugs investigated showed a proportinal relationship between diffusion speed and lipoid solubility. The effect of different membranes on the absorption experiments, with and without applied alternating pressure, was investigated. The results from the Sartorius Absorption Model and the Desaga Resomat II were compared.

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