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Correlation between lactate output and insulin secretion of the isolated perfused rat pancreas under the influence of high concentrations of phenformin

Loubatières, A.L.; Loubatières-Mariani, M.M.; Alric, R.; Blayac, J.P.; Valette, G.

Comptes Rendus des Seances de la Societe de Biologie et de ses Filiales 170(4): 828-832

1976

ISSN/ISBN: 0037-9026
PMID: 137050
Document Number: 101291
On the isolated perfused rat pancreas phenformin at high concentrations (10 mg/1, 50 mg/1 and 100 mg/1) provokes an increase of the insulin and lactate output in the effluent liquid. In no case is glucagon secretion modified by this substance. There exists a statistically significant correlations between the increase in insulin output and the increase in lactate output induced by phenformin.

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Loubatiéres-Mariani, M.M.; Blayac, J.P.; Alric, R.; Valette, G.; Loubatières, A. 1974: Effects of sodium DL lactate on secretion of insulin and glucagon. Study on the isolated perfused rat pancreas Comptes Rendus des Seances de la Societe de Biologie et de ses Filiales 168(8-9): 1038-1044
Howland, R.J.; Baroody, G.M. 1982: Differential inhibitory effects of noradrenaline upon insulin secretion by the isolated perfused pancreas of the rat Experientia 38(9): 1116-1118
Iversen, J. 1972: Gastrointestinal hormones and the secretion of glucagon and insulin from the isolated, perfused canine pancreas Israel Journal of Medical Sciences 8(6): 760
Hillaire-Buys, D.; Blayac, J.P.; Ribes, G.; Loubatières-Mariani, M.M. 1983: Effects of clonidine on the insulin secretion from the isolated, perfused pancreas of rats and newborn dogs Comptes Rendus des Seances de la Societe de Biologie et de ses Filiales 177(3): 332-337
Bierwolf, B.; Blech, W. 1976: Modification of insulin-secretion, induced by glucose, of the isolation-perfused rat pancreas using tolbutamide, glucosamine, diazoxide, glucagon and endogenous insulin Acta Biologica et Medica Germanica 35(5): 583-595
Iijima, F.; Yamagishi, F.; Iwatsuki, K.; Chiba, S. 1986: Effects of arterial pH and HCO-3 concentration on HCO-3 secretion in the isolated blood-perfused dog pancreas Archives Internationales de Pharmacodynamie et de Therapie 279(2): 314-323
Alric, R.; Loubatières-Mariani, M.M.; Loubatières, A.L.; Puech, R. 1972: Cholinergic receptors and glucagon secretion. Study on the isolated and perfused pancreas in rats Comptes Rendus des Seances de la Societe de Biologie et de ses Filiales 166(8): 1030-1033
Brunicardi, F.C.; Kleinman, R.M.; Ohning, G.; Lloyd, K.; Gingerich, R.; Wong, H.; Walsh, J. 1994: The inhibitory role of intraislet somatostatin on glucagon secretion in the isolated perfused human pancreas Transplantation Proceedings 26(6): 3451-3452
Basabe, J.C.; Rodriguez, R.R. 1971: Insulin secretion by the isolated pancreas Prensa Medica Argentina 58(24): 1247-1249
Maćkowiak, P. 1990: Amino acid--induced insulin release from the perfused rat pancreas. the influence of phenylalanine and tyrosine Acta Physiologica Polonica 41(7): 169-175
Sitozhevskiĭ, A.V.; Lusta, I.V.; Trofimov, A.V.; Ivanov, V.V.; Karpenko, O.A. 1994: Insulin secretion by isolated rat pancreas as affected by prooxidants; relationship to glutathione release Problemy Endokrinologii 40(3): 39-41
Fischer, U. 1971: Insulin effect on transmembranous glucose balance of the isolated perfused rat heart. 3. Behavior of glucose distribution space and intracellular glucose concentration in varying glucose supplies under influence of insulin Acta Biologica et Medica Germanica 27(1): 1-11
Ribes, G.; Valette, G.; Lignon, F.; Loubatières-Mariani, M.M. 1977: Lack of concordance in the effect of large doses of phenformin on insulin secretion and glycemia. Tentative analysis Comptes Rendus des Seances de la Societe de Biologie et de ses Filiales 171(4): 870-875
Petralito, A.; Lunetta, M.; Fiore, C.E.; Liuzzo, A.; Giuga, G. 1978: Influence of verapamil on blood sugar and insulin secretion after intravenous administration of glucose and on somatotropin secretion after insulin stimulation Bollettino Della Societa Italiana di Cardiologia 23(2): 404-411
Robberecht, P.; Christophe, J. 1970: Secretion of hydrolases by perfused fragments of rat pancreas Archives Internationales de Physiologie et de Biochimie 78(1): 172-174
Leclerc, L.; Fréminet, A.; Poyart, C.; Gentil, M.; Huel, C. 1979: Effects of alanine on the metabolism of lactate and glucose in the isolated perfused rat heart Pathologie-Biologie 27(4): 197-201
Saito, T.; Ishi, K. 1973: 84. the effects of calcium omission on the exocrine pancreatic secretion in the perfused rabbit pancreas Nihon Seirigaku Zasshi. Journal of the Physiological Society of Japan 35(8): 417
Kowalewski, K.; Kolodej, A. 1978: Secretory function of isolated canine pancreas perfused with fluorocarbon emulsion Surgery Gynecology and Obstetrics 146(3): 375-378
Lohmann, D.; Jahr, H.; Verlohren, H.J.; Zühlke, H. 1981: Causes of insulin secretion disorders in non-insulin dependent diabetics. Comparison of in vivo results with examinations of isolated islet cells Zeitschrift für die Gesamte Innere Medizin und ihre Grenzgebiete 36(2): 47-51
Kaygisiz, Z.; Akin, M.Z.; Basaran, A.; Günes, H.V.; Timuralp, B. 1991: The effect of lanthanum on the mechanical function of the isolated perfused rat heart at different extracellular calcium concentrations Acta Physiologica Hungarica 78(2): 191-200