Amino acid--induced insulin release from the perfused rat pancreas. the influence of phenylalanine and tyrosine
Maćkowiak, P.
Acta Physiologica Polonica 41(7): 169-175
1990
ISSN/ISBN: 0044-6033 PMID: 2136312 Document Number: 355590
The effects of L or D phenylalanine and L tyrosine on insulin release from the perfused rat pancreas were investigated. It was found that in the presence of D-glucose, all three amino-acids stimulate insulin secretion. After L-Phe had been removed from perfusate in the presence or absence of L-Tyr, the secondary rise of insulin release (an "off response") was noticed. This phenomenon did not follow to either D-Phe or L-Tyr.
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