Behavior of plasma/insulin, somatropin and NEFA after intravenous administration of tolbutamide in hepatic cirrhosis
Greco, A.V.; Ghirlanda, G.; Rebuzzi, A.; Altomonte, L.; Manna, R.
Minerva Medica 67(54): 3525-3532
1976
ISSN/ISBN: 0026-4806 PMID: 995300 Document Number: 98991
Cirrhotics presented higher insulin production, in the presence of a drop in glycaemia significantly less than controls, following 1 g of tolbutamide i.v. The drug also brought on a rapid drop in NEFA and a rise in plasma growth hormone. The pathogenesis of altered glucose tolerance in liver cirrhosis is discussed.
Document emailed within 1 workday
Related Documents
Quattrocchi, G.; Smedile, G.; Squillaci, S.; Grasso, E. 1974: Relations between carbohydrate loading and arteriosclerosis. I. Behavior of triglycerides and NEFA in relation to the blood sugar and IRi levels in normal subjects and in patients with cardiovascular diseases after intravenous administration of glucose Bollettino della Societa Italiana di Biologia Sperimentale 50(13): 930-935Gragnoli, G.; Tanganelli, I.; Signorini, A.M. 1980: Behavior of plasma insulin, C-peptide and glucagon in normal subjects and in patients with liver cirrhosis Bollettino della Societa Italiana di Biologia Sperimentale 56(1): 69-75
Malathy, K.; Kurup, P.A. 1973: Effect of administration of insulin and tolbutamide on the glycosaminoglycan levels in diabetic rat tissues Indian Journal of Biochemistry and Biophysics 10(1): 69-71
Pelkonen, R.; Taskinen, M.R.; Nikkilä, E.A. 1977: Response of plasma insulin to small doses of tolbutamide in obesity and acromegaly International Journal of Obesity 1(4): 315-324
Widström, A.; Cerasi, E. 1973: On the action of tolbutamide in normal man. 3. Interaction of tolbutamide with glucagon, aminophylline and arginine in stimulating insulin response Acta Endocrinologica 72(3): 532-544
Winkler, G.; Kolb, E.; Müller, I.; Leo, M.; Schulze, U.; Vallentin, G. 1990: The effect of intravenous administration of arginine and glycine on the blood plasma content of glucose, insulin, free fatty acids and total alpha-amino-N-compounds in lambs of different ages Archiv für Experimentelle Veterinarmedizin 44(3): 447-458
O'Keefe, S.J.; Abraham, R.; El-Zayadi, A.; Marshall, W.; Davis, M.; Williams, R. 1981: Increased plasma tyrosine concentrations in patients with cirrhosis and fulminant hepatic failure associated with increased plasma tyrosine flux and reduced hepatic oxidation capacity Gastroenterology 81(6): 1017-1024
Ahuja, M.M.; Shanker, P.U.; Garg, V.K. 1972: Different clinical types of Indian diabetics: characterization based on response of immuno-reactive plasma insulin to glucose and tolbutamide load Indian Journal of Medical Research 60(1): 123-131
Said, A.; Müller, I.; Kolb, E.; Gründel, G.; Schmidt, U.; Schineff, C.; Gottschild, C.; Vallentin, G. 1986: The effect of intravenous administration of butyrate, isobutyrate, isovalerate and capronate to calves, young cattle and cattle on the blood plasma levels of glucose, insulin, free fatty acids and total alpha-amino-nitrogen Archiv für Experimentelle Veterinarmedizin 40(2): 183-194
Kouider, S.; Kolb, E.; Müller, I. 1980: Effect of the intravenous administration of a sorbitol solution on the blood plasma content of sorbitol, fructose, glucose, insulin and free fatty acids as well as on the sorbitol half-life in calves, young and adult cattle Archiv für Experimentelle Veterinarmedizin 34(2): 193-203
Petralito, A.; Lunetta, M.; Fiore, C.E.; Liuzzo, A.; Giuga, G. 1978: Influence of verapamil on blood sugar and insulin secretion after intravenous administration of glucose and on somatotropin secretion after insulin stimulation Bollettino Della Societa Italiana di Cardiologia 23(2): 404-411
Reitano, R.; Barbagallo, F.; Ragusa, E.; Valenti-Milito, M. 1989: Behavior of angiotensin-converting enzymes in hepatic cirrhosis Recenti Progressi in Medicina 80(1): 46-47
Rubio Pérez, P.; de Pablos Mateos, I.; Gallardo López, J.; Sánchez Sánchez, M.L. 1982: Changes in plasma levels of gonadotropins in men with hepatic cirrhosis Revista Clinica Espanola 167(5): 317-320
Bierwolf, B.; Blech, W. 1976: Modification of insulin-secretion, induced by glucose, of the isolation-perfused rat pancreas using tolbutamide, glucosamine, diazoxide, glucagon and endogenous insulin Acta Biologica et Medica Germanica 35(5): 583-595
Adami, G.F.; Vita, M.; Cingolani, B.; Griffanti-Bartoli, F. 1980: Behavior of non-esterified fatty acids (NEFA) after surgical operations Minerva Chirurgica 35(12): 929-933
Iatsenko, V.N.; Muranevich, V.V. 1976: Intravenous administration of insulin to diabetic patients during surgical interventions Khirurgiia 6: 151-155
Farooq, O.; Isenberg, J.I. 1975: Effect of continuous intravenous infusion of insulin versus rapid intravenous injection of insulin on gastric acid secretion in man Gastroenterology 68(4 Pt 1): 683-686
Marañón, A.; Durán, S.; Sanjose, G.; Romero, E. 1974: Glucose tolerance, insulin secretion, levels of free fatty acids and growth hormone in hepatic cirrhosis Revista Clinica Espanola 132(4): 299-306
Rodríguez Bueno, S.; Ordi Ros, J.; Vilardell Tarrés, M.; Vicente Aranguena, P.; García-Bragado Dalmau, F.; Bosch Gil, J.; Villar Casares, M.; Alijotas Reig, J. 1985: Level of plasma fibronectin in patients with hepatic cirrhosis. its relation to coagulation factor V Medicina Clinica 85(18): 746-748
Giordano, G.; Marugo, E. 1974: Behavior of blood gastrin in humans after intravenous administration of cortisol Bollettino della Societa Italiana di Biologia Sperimentale 50(22): 1905-1910